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173,000+ PubMed Studies

The Science of Glutathione

Glutathione is the protector and detoxifier of the cell — the key to life, health, performance, protection, and longevity of every human cell.

The Master Antioxidant

What is Glutathione?

Glutathione is the body's most powerful natural antioxidant — produced in every cell and responsible for detoxification, immune function, and cellular protection across virtually every system in the body.

Unlike other antioxidants, glutathione is unique in its ability to recycle itself — regenerating other antioxidants like Vitamins C and D and amplifying their effectiveness throughout the body.

With over 173,000 studies on PubMed (compared to ~73,000 for Vitamin C), glutathione is one of the most comprehensively studied molecules in the history of biomedical science.

173K+
PubMed Studies
vs 73K for Vitamin C
3
Amino Acid Building Blocks
Glycine, cysteine, glutamic acid
100%
Cellular Presence
Found in every human cell
↓ 40%
Decline by Age 60
Continuous depletion from birth

Documented Benefits

Six Transformative Benefits

Backed by decades of peer-reviewed research from institutions worldwide.

🛡

Strengthened Immune System

Glutathione neutralizes free radicals and protects the body from their harmful effects. It reduces inflammation and supports the body's natural ability to fight infection. It also plays a role in the synthesis of new immune cells, keeping your immune system functioning at its peak.

Increased Energy

Supplementing with glutathione helps reduce fatigue and improve energy levels. As an antioxidant, it reduces oxidative damage caused by free radicals. Glutathione also supports the production of ATP — the body's cellular energy currency.

🏃

Enhanced Stamina & Endurance

Glutathione helps the body transform vitamins and minerals into energy, allowing for greater endurance and longer periods without fatigue. It also detoxifies cells, allowing for better performance across physical and mental domains.

Improved Exercise Recovery

Glutathione is a natural antioxidant that plays an important role in exercise recovery. It reduces oxidative damage that occurs after physical activity, which can lead to faster recovery times and improved training adaptation.

🧠

Greater Mental Clarity & Focus

Glutathione protects brain cells, reduces neuroinflammation, and improves overall brain health. It is an important factor in improving learning and intellectual functioning, and can protect the brain from the damaging effects of free radicals.

Enhanced Quality & Length of Life

Studies show that higher glutathione levels help reduce the damaging effects of oxidative stress — a major contributor to aging and related illnesses. Higher glutathione levels are associated with a healthier, more enjoyable, and longer life.

The Depletion Problem

Aging and Glutathione

Your glutathione levels decrease the longer you are alive. Continuous attacks on your cells by toxins, heavy metals, radiation, and free radicals cause damage and accelerate the aging process.

Glutathione levels are further reduced by trauma the cells encounter — injuries, infections, and disease all deplete your body's most critical antioxidant reserve.

Higher glutathione levels are associated with an extensive number of health, performance, and anti-aging benefits — making consistent supplementation essential for maintaining optimal levels as we age.

Glutathione Levels by Age

Ages 20–30100%
Peak levels
Ages 30–4080%
Early decline begins
Ages 40–5065%
Accelerating depletion
Ages 50–6050%
Significant reduction
Ages 60+35%
Critical deficiency range

Approximate relative glutathione levels. Individual results vary.

Peer-Reviewed Evidence

Published Research

Key studies from leading biomedical journals that demonstrate the science behind glutathione supplementation.

2015European Journal of Nutrition

Randomized controlled trial of oral glutathione supplementation on body stores of glutathione

Richie JP Jr, et al.

Oral glutathione supplementation effectively increased body stores of glutathione and enhanced markers of immune function and oxidative stress reduction.

View on PubMed
2014Integrative Medicine (Encinitas)

Glutathione!

Pizzorno J.

Comprehensive review establishing glutathione as the most important molecule for maintaining health and preventing disease, aging, and cancer.

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1992European Journal of Clinical Pharmacology

The systemic availability of oral glutathione

Witschi A, et al.

Foundational study examining oral glutathione bioavailability and the challenges of conventional delivery methods for effective supplementation.

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2009Molecular Aspects of Medicine

Glutathione: overview of its protective roles, measurement, and biosynthesis

Forman HJ, et al.

Glutathione plays critical protective roles in detoxification, antioxidant defense, and regulation of cellular processes essential for health.

View on PubMed
2019Nutrients

A Review of Dietary (Phyto)Nutrients for Glutathione Support

Minich DM, Brown BI.

Identified key dietary nutrients and phytochemicals that support glutathione status, highlighting the importance of maintaining optimal levels.

View on PubMed

Research Library

173,000+

Studies on PubMed

Glutathione is one of the most studied molecules in the history of biomedical science — with more than twice the research volume of Vitamin C on the world's leading biomedical database.

Explore more published research on glutathione and HydraStat™ technology through the world's largest biomedical research database.